hmmIBD

Author

Steve Schaffner

Published

December 11, 2023



Summary sheet

Main use-cases Estimating relatedness between parasites, detecting selective sweeps
Authors Stephen Schaffner
Latest version V2.1.1
License GPL-3.0 license
Website none
Code repository https://github.com/glipsnort/hmmIBD.git
Publication https://doi.org/10.1186/s12936-018-2349-7
Tutorial authors Steve Schaffner
Tutorial date 11 December, 2023

Purpose

hmmIBD implements a hidden Markov model (HMM) for detecting genomic regions that are identical by descent (IBD) for pairs of haploid samples. It was written to find large IBD regions in sequenced haploid P. falciparum genomes, but it can be applied to other organisms (including phased diploids) and can find shorter IBD regions as well. The package includes scripts to extract data from a VCF file into the appropriate format and to thin markers for better performance.

Existing resources

Citation

``` @article{, title = {hmmIBD: software to infer pairwise identity by descent between haploid genotypes}, author = {Schaffner, S.F., Taylor, A.R, et al.}, journal = {Malaria Journal}, volume = 17, pages = 196 year = 2018, doi = {https://doi.org/10.1186/s12936-018-2349-7} }

Back to top